The cutaneous epidermal growth factor network: Can it be translated clinically to stimulate hair growth?
Authors: Alexandrescu DT, Kauffman CL, Dasanu CA The influences exerted by the epidermal growth factor receptor (EGFR) on the skin act at multiple levels, which involve compartments that normally express EGFR. These include the basal and suprabasal layers of the epidermis, sebaceous glands, and the outer root sheath of the hair follicles. The physiological roles of EGFR ensure epidermal renewal and integrity, along with a gatekeeping and function and hair growth stimulation functions.
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The cutaneous epidermal growth factor network: Can it be translated clinically to stimulate hair growth?
Persistent hair growth during treatment with the EGFR inhibitor erlotinib.
Authors: Alexandrescu DT, Kauffman CL, Dasanu CA Medications belonging to the group of epidermal growth factor (EGFR) inhibitors are currently in widespread use for the treatment of epithelial malignancies. Many cutaneous side effects are known to develop as a result of the use of these agents. Trichomegaly is a newly described side effect, consisting of premature maturation (terminal differentiation) of the hair of the eyelashes and the scalp, which is characterized by a hairy phenotype.
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Persistent hair growth during treatment with the EGFR inhibitor erlotinib.
Empirical Discovery Yields Treatment for Sparse Eyelashes
(Source: AWHONN Lifelines)
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Empirical Discovery Yields Treatment for Sparse Eyelashes
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